Sheffield Institute for Nucleic Acids

Seminars and Events

We host a number of seminars and events throughout the year. These are generally informal, open to everyone and are a great chance to catch up with SInFoNiA members and colleagues from across the University.

SInFoNiA Symposium

Our Bi-annual Research Symposium will take place on March 21st 2019 at the Edge in Sheffield. Stay tuned for more details!

SInFoNiA Seminar Series

We regularly host external Seminars on topics spanning the breadth of research interests in SInFoNiA. Details of upcoming seminars will be announced here.

Our next Seminar will take place on Friday February 1st at 10am in the Alfred Denny Building conference room.

 

Visualising the matrix: New tools for network-based analyses of complex data

Prof. Tom Freeman, Systems Immunology Group, The Roslin Institute, University of Edinburgh

Visualising the matrix: New tools for network-based analyses of complex data

Prof. Tom Freeman, Systems Immunology Group, The Roslin Institute, University of Edinburgh

 

Biological data continues to grow in size and complexity. Whilst the many omics analysis platforms generate data on different molecular species, the end result is often largely the same – vast tables of numerical values, and its analysis and interpretation remain a significant challenge.

I will discuss our work over the past decade combining the use of gaming technology, maths and software engineering to rapidly construct vast networks from data, in order visualise, explore and interpret the underlying biology. Originally, our work focused on transcriptomics data where we developed the software, BioLayout Express3D, to turn transcriptomics data into large gene correlation networks where they could be explored in 3-D space and clustered to discover expression modules associated pathways or cell types.

More recently, we have been reimagining network analysis, building a new analysis platform called Graphia. This is faster, more scalable (1,000,000s of data points), includes dynamic rendering and a very much extended range of new functionality for network analysis. We have also been exploring the utility of Graphia in the analysis of different biological data types where the challenges are similar but not the same, including single cell, genotyping, imaging and multi-parametric flow cytometry data. I will highlight the advantages of network analysis over other approaches to pattern finding and visualising similarity matrices.

Research Discussions Seminars

The SInFoNiA Research Discussions seminar series is an informal series of meetings that showcase research within the Institute. We host presentations from PI’s, Postdocs and PhD students, and topics range from work-in-progress talks to polished research presentations – however all talks are based around a vibrant discussion of the topics raised. Presentations are followed by pizza, beer and networking. Everyone is welcome at these meetings, and they are a great place to network and find out about the work happening in SInFoNiA.

Research Discussion take place at 4pm on the last Tuesday of each month in the Alfred Denny Building Conference Room.

Our next research discussions meeting will take place on Tuesday February 26.

Meeting Schedule

Previous meetings